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Etilevodopa hydrochloride

CAS No. 39740-30-2

Etilevodopa hydrochloride( Etilevodopa HCl | ?L-DOPA ethyl ester | Levodopa ethyl ester )

Catalog No. M27765 CAS No. 39740-30-2

Etilevodopa HCl is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Etilevodopa hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Etilevodopa HCl is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.
  • Description
    Etilevodopa HCl is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.
  • In Vitro
    Etilevodopa (L-Dopa ethyl ester) hydrochloride passes unchanged through the stomach to the duodenum, where it is rapidly hydrolyzed by local esterases to Levodopa and ethanol, and is subsequently absorbed into the blood stream as Levodopa.Compared with standard Levodopa, Etilevodopa hydrochloride has greater solubility in the stomach, faster passage to the small intestine, and a shortened time to maximum Levodopa concentration.
  • In Vivo
    ——
  • Synonyms
    Etilevodopa HCl | ?L-DOPA ethyl ester | Levodopa ethyl ester
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    nNOS/NOS1 AP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    39740-30-2
  • Formula Weight
    261.7
  • Molecular Formula
    C11H16ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 125 mg/mL (477.65 mM)
  • SMILES
    Cl.CCOC(=O)[C@@H](N)Cc1ccc(O)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wan-Hung Lee, et al. ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability. Mol Pain. 2018 Jan-Dec;14:1744806918801224.
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